Full-length 16S rRNA gene sequencing by PacBio improves taxonomic resolution in human microbiome samples.

Notably, the Streptococcus genus had higher mean relative abundance (not significant) in PacBio than in Illumina platform in saliva and subgingival plaque biofilm samples whereas other relevant genera known to be oral pathogens like Fusobacterium, Leptotrichia and Treponema showed a trend for lower relative abundance ( p < 0.05, adjusted p -value > 0.05) (Fig. 3 ).

also in 53,322 other papers