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Improving CRISPR-Cas9 directed faithful transgene integration outcomes by reducing unwanted random DNA integration.

J Biomed Sci · 2024 · PMC10964699 · PMID 38532479

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The initial transgene integration efficiencies of each strategy indicate that the matched end joining and long homology arms strategies both had more efficient transgene integration than the unmatched end joining strategy and donor control, although these differences did not reach statistical significance (Fig. 3 A).

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