Modeling 5-FU-Induced Chemotherapy Selection of a Drug-Resistant Cancer Stem Cell Subpopulation.

Although the difference did not reach statistical significance at all time points, our analysis revealed the increased presence of the CD24-ABCG2+ ALDH1+ population after 5-FU treatment, indicating that this population was resistant to the chemotherapeutic agent ( Figure 3 C and Supplementary Figure S1C ).

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