Neurofilament Light Chain Concentration in Cerebrospinal Fluid in Children with Acute Nontraumatic Neurological Disorders.

Children (Basel) · 2024 · PMC10969464 · PMID 38539395

Europe PMC DOI

hedged sentences

0.0820

closest p · 1.6× alpha

0.0820

boldest claim

The sentences

a clear trendp = 0.082so close (0.05 < p ≤ 0.1)

Comparing cNfL levels in children with Lyme neuroborreliosis to those with Bell’s palsy, there was a clear trend toward higher cNfL levels in Lyme neuroborreliosis, but this did not reach a significance level ( p = 0.082; Figure 2 B).

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highly significantno p-value reported

speculated whether NfL might be a useful biomarker of response to LNB treatment, as their study in adults revealed a highly significant decrease of plasma NfL at 3 and 6 months after antibiotic treatment of LNB [ 26 ].

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