Although this difference was only marginally significant, it suggests that the sensitivity and negative predictive value (NPV) of HPV16 E6 serology within the context of HIV-positive MSM individuals—a demographic at a higher risk for AC—may be lower.
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Assessing the Potential of HPV16 E6 Seroprevalence as a Biomarker for Anal Dysplasia and Cancer Screening-A Systematic Review and Meta-Analysis.
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