Interestingly, the inhibition of dynamin-dependent endocytosis with dynasore failed to inhibit AAV2 uptake in HEK293T cells and, instead, showed a trend towards increased transduction [ 47 ].
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Natural Adeno-Associated Virus Serotypes and Engineered Adeno-Associated Virus Capsid Variants: Tropism Differences and Mechanistic Insights.
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