For vitamin B1 in total populations ( Figure 4A ), compared to the T1 (reference: 1), the risk of sarcopenia decreased by 25 and 31% for T2 and T3, respectively, with a significant trend ( P trend = 0.037).
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Association of vitamins B1 and B2 intake with early-onset sarcopenia in the general adult population of the US: a cross-sectional study of NHANES data from 2011 to 2018.
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Since B vitamins are directly or indirectly involved in a variety of biological processes, including energy and protein metabolism, maintenance of neurological function, and even relatively short-term deficiencies may accumulate detrimental effects, their contribution to the complex etiology of sarcopenia may be significant and may vary with its stage.