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The tumor suppressor p53 is a negative regulator of the carcinoma-associated transcription factor FOXQ1.

J Biol Chem · 2024 · PMC10981115 · PMID 38432629

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Among CRC cell lines included in the Cancer Cell Line Encyclopedia, increased FOXQ1 levels were observed in cells with individual or combined mutation of TP53 and APC , although these changes did not reach statistical significance ( Fig. 3 H ).

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