moderately significantp < 0.1
Further, therapeutic mode of OLP treatment showing the reduced mRNA expression of downstream effectors of PI3K-Akt1 signaling markers CD40 (p < 0.01; significant), AKT (p < 0.001; highly significant), NF-κB (p < 0.01; significant), and Bim (p < 0.1 moderately significant) indicated that the death of antigen-stimulated macrophages was independent of CD40/NF-κB signaling ( Figure 1 B).