Lactate transporter MCT1 in hepatic stellate cells promotes fibrotic collagen expression in nonalcoholic steatohepatitis.

The hepatocyte-selective MCT1KO caused increased total fibrosis, evidenced by trichrome staining of liver ( Figure 7D and E ), while the stellate cell MCT1KO was associated with a trend toward diminished trichrome staining that did not reach statistical significance ( Figure 7D and E ).

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