Biodegradable Zn-5Dy Alloy with Enhanced Osteo/Angio-Genic Activity and Osteointegration Effect via Regulation of SIRT4-Dependent Mitochondrial Function.

Following 30 d of immersion, the mechanical properties of the HR samples showed a decreasing trend with increasing Dy content at various levels.

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For HUVECs, the cell viability of all groups was higher than 100% except for the 75% concentration extract of the pure Zn group, and the cell viability of different concentrations of Zn–1Dy groups showed a trend of first increasing and then decreasing with an increase in Dy content.

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