Genomic characterization and pathogenicity of a novel fowl adenovirus serotype 11 isolated from chickens with inclusion body hepatitis in China.

The difference between the viral loads in the liver and pancreas from infected 1-wk-old and 2-wk-old chickens did not reach statistical significance ( p = 0.4310 and 0.0963, respectively) ( Figure 7 ).

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In recent years, outbreaks of IBH have exhibited an increasing trend worldwide and have caused substantial economic losses in many countries ( Helmboldt and Frazier, 1963 ; Gomis et al., 2006 ; Wilson et al., 2010 ; Nakamura et al., 2011 ; Steer et al., 2015 ; Zhao et al., 2015 ; Oliver-Ferrando et al., 2017 ; Morshed et al., 2017 ; Mohamed et al., 2018 ; Huang et a

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