An increase in CD4 + Ki67 + T cells and NK + Ki67 + cells in tumor of mXTX301 treated group was also observed, although it did not reach statistical significance.
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XTX301, a Tumor-Activated Interleukin-12 Has the Potential to Widen the Therapeutic Index of IL12 Treatment for Solid Tumors as Evidenced by Preclinical Studies.
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