Expanding the Use of HIPEC in Ovarian Cancer at Time of Interval Debulking Surgery to FIGO Stage IV and After 6 Cycles of Neoadjuvant Chemotherapy: A Prospective Analysis on Perioperative and Oncologic Outcomes.

6 However, an almost significant increased number of overall and severe postoperative complications was identified in FIGO stage III with respect to FIGO stage IV patients. 6 Similarly, a trend toward a significant increased number of G3–G5 postoperative complications was detected in women receiving > 4 cycles of NACT.

also in 1,004 other papers

Neither FIGO stage at diagnosis nor number of received NACT cycles appeared to affect perioperative outcomes, even if women submitted to > 4 cycles of NACT showed a trend toward a more deranged postoperative creatinine serum level and longer median hospital stay, which can be explained by (i) the higher rate of small/large bowel resection perfomed in this popualtion, (ii) by the cumulative toxicity from chemotherapy, and/or (iii) by the usual higher rate of comorbid

also in 33,481 other papers