Shear-wave elastography to predict hepatocellular carcinoma after hepatitis C virus eradication: A systematic review and meta-analysis.

Research results LS at baseline and 12 wk follow-up showed a trend towards greater values in those who will develop HCC compared to those who will not [baseline LS standardized mean difference (SMD): 1.15, 95% confidence interval (95%CI): 020-2.50; LS SMD after 12 wk: 0.83, 95%CI: 0.33-1.98].

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The quantitative analysis of the remaining four studies showed a positive trend between higher LS values, measured in kPa, and risk of developing HCC, although statistical significance was not reached at EOT and 12 wk of follow-up, while LS at 24 wk showed a statically significant association with HCC development.

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