The broad impact of cell death genes on the human disease phenome.

The most highly significant association was between CASP8 expression and “Other malignant neoplasms of skin”.

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To enrich for potential additional relevant patterns, we graphed median effect sizes for nominally significant ( p unadj <0.05) gene/trait associations alongside the significant gene/trait associations (as denoted by asterisks, Fig. 4B ).

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