A targeted proteomics method for quantifying plasma apolipoprotein kinetics in individual mice using stable isotope labeling.

Plasma triglyceride concentrations tended to be higher in Ldlr −/− mice than the WT mice but the difference did not reach statistical significance P = 0.07), and plasma cholesterol concentrations were significantly higher in Ldlr −/− mice than in WT mice but significantly lower than in the Apoe −/− mice.

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