The Impact of Radiofrequency Ablation on Survival Outcomes and Stent Patency in Patients with Unresectable Cholangiocarcinoma: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

While overall survival was not different between the groups (HR 0.62; 95% CI 0.36–1.07; p = 0.09; I 2 = 80%;), the subgroup analysis of studies employing plastic stents showed a trend toward better survival in the RFA-treated group (HR 0.42; 95% CI 0.22–0.80; p = 0.009; I 2 = 72%).

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Our primary findings reveal a notable trend toward improved OS for patients treated with RFA in conjunction with plastic stents, along with improved stent patency in the RFA-treated group.

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