Similarly, we observed a significant decrease in Nrf2 activity, as indicated by DNA binding ability in nuclear extracts, in the cortex and a nearly significant reduction in Nrf2 activity in the liver ( Figure 1 B,C). 3.2.
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Accelerated Aging Induced by an Unhealthy High-Fat Diet: Initial Evidence for the Role of Nrf2 Deficiency and Impaired Stress Resilience in Cellular Senescence.
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