Efficacy and Safety of Umbilical Cord-Derived Mesenchymal Stromal Cell Therapy in Preclinical Models of Sepsis: A Systematic Review and Meta-analysis.

In the one large animal (pig) model, mortality was lower in the MSC group as compared to the control group (2/6 [33%] vs 6/6 [100%]), but it did not reach statistical significance. 37 Other potential sources of heterogeneity include the timing of MSC administration as well as the administration of fluid and antibiotic resuscitation.

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