Induction of durable remission by dual immunotherapy in SHIV-infected ART-suppressed macaques.

Effector function for the N-803+10-1074 group was increased by 3.2-fold ( P =0.11), whereas suppressive activity for the N-803+10-1074+3BNC117 group was 12.6 times higher and highly significant by the Wald test ( P =9.9×10 −14 ) ( fig.

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A faster pharmacokinetic (PK) clearance of 10-1074 was observed in RMs that also received N-803 administration, although this did not reach statistical significance ( fig.

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