Diagnostic yield after next-generation sequencing in pediatric cardiovascular disease.

HGG Adv · 2024 · PMC11024993 · PMID 38521975

Europe PMC DOI

hedged sentences

0.0710

closest p · 1.4× alpha

0.0710

boldest claim

The sentences

approached significancep = 0.071so close (0.05 < p ≤ 0.1)

There was no significant relationship between the rates of CNVs and indels/SNVs with the phenotypic subtypes of CHD; for CTDs, this approached significance, with 17/34 (50%) participants with a CTD having a causative indel/SNV compared to 59/87 (68%) of patients without a CTD having one ( p = 0.071; Table S7 ).

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highly significantno p-value reported

Our results showed a highly significant increase in diagnostic rate for GS compared to ES and for syndromic cardiac defects compared to isolated cardiac defects.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.