Early altered directionality of resting brain network state transitions in the TgF344-AD rat model of Alzheimer's disease.

Front Hum Neurosci · 2024 · PMC11026683 · PMID 38646161

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.0500

boldest claim

The sentences

did not reach statistical significancep > 0.05actually significant

Where the interaction effect between age and genotype did not reach statistical significance ( p > 0.05), it was excluded prior to assessing main effects of age and genotype.

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a decreasing trendno p-value reported

Support for this hypothesis can be found in another study (Ma et al., 2020 ), where CAPs were studied in healthy elderly participants, patients with mild cognitive injury (MCI), and AD patients, showing that average dwell time in the DMN-like CAP showed a decreasing trend in AD.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.