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A Comprehensive Review of Novel FDA-Approved Psychiatric Medications (2018-2022).

Cureus · 2024 · PMC11028406 · PMID 38646400

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showed a trendno p-value reported
The results showed a trend for a dose-related improvement in symptoms of depression as determined by the mean reduction of 11.2 points in the MADRS total score for patients in the lumateperone group, while patients in the placebo group had a mean reduction of 6.6 points [ 41 ].

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