Culture substrate stiffness impacts human myoblast contractility-dependent proliferation and nuclear envelope wrinkling.

Specifically, on FN and LAM substrates, GoF was low at 2 kPa, increased at 6 kPa and then remained relatively constant at 38 kPa, although the increase on LAM substrates was more subtle, and did not reach statistical significance in our study ( Fig. 2C ).

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