The biased apelin receptor agonist, MM07, reverses Sugen/hypoxia-induced pulmonary arterial hypertension as effectively as the endothelin antagonist macitentan.

Front Pharmacol · 2024 · PMC11035786 · PMID 38655187

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MM07 also significantly reversed pulmonary vessel muscularisation and showed a trend towards reducing the incidence of neointimal lesions.

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