Nonlinear relationship between viral load and TCT in single/multiple HPV52 infection.

For HPV52 viral load, with an increase in HPV52 viral load, there was a significant rise of 25.5% (OR: 1.255, 95% CI: 1.114–1.415) in the risk of TCT results (LSIL or worse), indicating a highly significant statistical significance( P < 0.001) (Table 2 ).

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With increasing age, the risk of TCT results (LSIL or worse) also increased, although it did not reach statistical significance (all P > 0.05).

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When the LOG viral load was prior to the inflection point, the risk of TCT results (LSIL or worse) did not increase, but instead exhibited a decreasing trend (OR:0.768 95% CI: 0.588–1.004); whereas, the risk of TCT abnormality increased 2.025-fold after the load exceeded 12.095.

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