The gut microbiome-prostate cancer crosstalk is modulated by dietary polyunsaturated long-chain fatty acids.

While human PCa FMT1 and FMT6 showed a trend to increase (734 ± 30% and 63 ± 22%, respectively) TRAMP-C2 tumour mass compared to autologous mouse FMT, FMT2, 3, 4 and 5 all led to bigger tumours (127 ± 4% p = 0.006, two-sided t -test, 199 ± 13% p = 0.007, two-sided t -test, 247 ± 26% p = 0.04, two-sided t -test and 166 ± 15% p = 0.01, two-sided t-test, respectively) in the recipient animals (Fig. 3c ).

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