25) Although the data on central aortic pressure is marred by a lack of data on this parameter compared to the peripheral blood pressure (BP), whatever limited data is there, there is a clear trend that central aortic pressure does predict cardiovascular disease and events better than the peripheral BP. 26) Further, a meta-analysis of 13 randomized controlled trials on hypertension showed that beta blockers were associated with a 16% increased risk of stroke compared to CCBs and ARBs with no difference in MI.
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