Comparison of the effect of treatment with NSAIDs added to anti-TNF therapy versus anti-TNF therapy alone on the progression of structural damage in the spine over 2 years in patients with radiographic axial spondyloarthritis from the randomised-controlled CONSUL trial.

The mean mSASSS change over 2 years of treatment in the ITT analysis was numerically higher in the monotherapy group (1.7; 95% CI 0.8 to 2.6) when compared with the combination therapy group (1.1; 95% CI 0.4 to 1.8) ( figure 3A ), although this difference did not reach statistical significance (p=0.79).

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