The impact of continuous and intermittent ketogenic diets on cognitive behavior, motor function, and blood lipids in TgF344-AD rats.

TgF344-AD animals demonstrated impaired spatial learning memory that was not mitigated by diet At 8 months of age, Tg males on a CD showed spatial learning memory impairment during the training phase as assessed by the Barnes maze ( Figure 5A , p < 0.05), while 12-month-old males showed a strong trend toward impaired spatial learning memory ( Figure 5B , p = 0.068) compared to WT.

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