Fluorescence Lifetime Imaging of Human Retinal Pigment Epithelium in Pentosan Polysulfate Toxicity Using Adaptive Optics Scanning Light Ophthalmoscopy.

36 The long FL peak of τ m , τ 1 , and τ 2 of PPS toxicity histograms showed a clear trend of greater FL prolongation with increasing ROI disease severity.

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However, even with a small cohort, an obvious trend of prolonged lifetimes in ROIs with greater RPE degeneration is seen.

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