Tgif1-deficiency impairs cytoskeletal architecture in osteoblasts by activating PAK3 signaling.

Elife · 2024 · PMC11045221 · PMID 38661167

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Confirming this observation in vivo, expression of Pak3 mRNA showed a trend towards an increase in bones from Tgif1 -/- mice compared to control littermates ( Figure 3C ).

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