In addition, in our opinion, a clear trend is delineated towards progressively increasing use of advanced data analysis methodologies (including mathematical modelling) in the clinical practice, since precision medicine recommendations emphasize the need for individual, personalized diagnostics, treatment and general care ( 25 – 28 ).
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Glucagon kinetics assessed by mathematical modelling during oral glucose administration in people spanning from normal glucose tolerance to type 2 diabetes.
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The fact that several factors may be significant determinants of glucagon levels appears also consistent with the findings of one of our previous studies on glucagon involving the different macronutrients ( i.e. , glucose, proteins and fat) ( 45 ).