Maternal obesity increases the risk of hepatocellular carcinoma through the transmission of an altered gut microbiome.

Female offspring of obese mothers showed a trend towards increased fat mass, measured by EchoMRI at 8 weeks (3.2 vs. 2.5 g, p = 0.093), with no statistical difference at 40 weeks; there were no differences in male offspring at any time point ( Fig. 1 C).

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