nominally significantp = 1.04 × 10 −2
Causal Effects of Redox Regulatory Drug Targets on Psychiatric Disorders According to a significance threshold of p < 5.78 × 10 −6 for the eQTL level and p < 1.49 × 10 −4 for the pQTL level, genetic variations in the vitamin C target (cofactor, OGFOD2 in cerebellum, OR = 0.784, 95% CI = 0.715–0.859, p = 2.14 × 10 −7 ) and the melatonin target (agonist, RORB in cerebellum, 1.263, 95% CI = 1.167–1.368, p = 8.80 × 10 −9 ; additionally, there were many nominally significant results which could confirm the above results: hypothalamus, p = 1.04 × 10 −2 ; putamen basal ganglia, p = 4.40 × 10 −3 ) were significantly related to the risk of SCZ.