Mitochondrial and Nuclear DNA Variants in Amyotrophic Lateral Sclerosis: Enrichment in the Mitochondrial Control Region and Sirtuin Pathway Genes in Spinal Cord Tissue.

Biomolecules · 2024 · PMC11048214 · PMID 38672428

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slightly significantno p-value reported

We observed a slightly significant CN-mtDNA enrichment in ALS in the WGS dataset, for which the mtDNA-CN estimation is more reliable [ 133 ]. 5.

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