Proteomic Analysis of Spatial Heterogeneity Identifies HMGB2 as Putative Biomarker of Tumor Progression in Adult-Type Diffuse Astrocytomas.

Cancers (Basel) · 2024 · PMC11049315 · PMID 38672598

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did not reach statistical significancep = 0.06so close (0.05 < p ≤ 0.1)

Similar to our initial proteomic analysis, HMGB2 expression was slightly higher in the HG areas (mean score = 69.37) compared to the LG areas (mean score = 63.43) within single tumors ( Figure 4 b,c), but this difference did not reach statistical significance ( p = 0.06).

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