Feasibility and Preliminary Efficacy of American Elderberry Juice for Improving Cognition and Inflammation in Patients with Mild Cognitive Impairment.

As shown in Figure 3 c, A2M levels for the elderberry condition at 6 months were significantly higher than baseline [ t (20.00) = −2.73, p = 0.01, g av = 0.78, moderate–large effect], and trending towards significance for higher values than 3 months [ t (20.00) = −1.99, p = 0.06, g av = 0.24, small effect] in post hoc comparisons.

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At 6 months, results showed a trend towards significance for lower values in the placebo–control group relative to elderberry [ t (32.00) = −1.84, p = 0.08, g av = 0.95, large effect].

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At 6 months, results showed a trend towards significance for lower values in the placebo–control group relative to elderberry [ t (32.00) = −1.84, p = 0.08, g av = 0.95, large effect].

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