Regional antibiotic delivery for sternal wound infection prophylaxis a systematic review and meta-analysis of randomized controlled trials.

Superficial SWIs data were available from 8 studies: RAD was associated with a significant, over 45% reduction of the odds of SSWI: OR (95%CIs): 0.54 (0.32–0.90); p = 0.01; I 2 = 63%; that reached borderline significance in gentamicin studies (0.55 (0.30–1.01); p = 0.05; I 2 = 70%; P heterogeneity for between subgroups comparison = 0.71.

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