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Comparison of Effectiveness Among Different Sodium-Glucose Cotransoporter-2 Inhibitors According to Underlying Conditions: A Network Meta-Analysis of Randomized Controlled Trials.

J Am Heart Assoc · 2024 · PMC11056162 · PMID 38293914

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53 In the presentstudy, whereas a similar pattern was seen, it did not reach statistical significance. 42 It has been controversial whether SGLT2 inhibitors increase the risk of limb amputation.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.