Nevertheless, there was a notable trend for upregulation in nCI-PD (Supplementary Figs.
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Mitochondrial complex I deficiency stratifies idiopathic Parkinson's disease.
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Lower proportions of CI intact neurons were also seen in the internal globus pallidus and the subiculum, but these did not reach statistical significance.
This analysis showed a highly significant enrichment in OXPHOS- and ribosome related pathways in excitatory neurons (Supplementary Data 13 ).