Although no significant difference was observed in the risk of stroke or systemic embolism between DOACs and VKAs, DOACs showed a trend toward lower all-cause mortality and major bleeding events.
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Comparison of Effectiveness and Safety of Direct-Acting Oral Anticoagulants and Vitamin K Agonists in Patients With Atrial Fibrillation and End-Stage Kidney Disease: A Systematic Review and Meta-Analysis.
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