Calculation of the M2 score to assess M2 macrophage infiltration revealed an increasing trend in the N1b group, although statistical significance was observed in neither the CHA nor TCGA databases ( P =0.063 and P =0.553, respectively) ( Fig. 1B , E ).
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Clinicopathological Features and Molecular Signatures of Lateral Neck Lymph Node Metastasis in Papillary Thyroid Microcarcinoma.
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In a recent meta-analysis of 33 studies on PTMC, there was a tendency for an increased risk of LLNM in BRAF V600E -mutated PTMC, although it did not reach statistical significance [ 25 ], which is consistent with our study.