Neuroprotective effects of niclosamide on disease progression via inflammatory pathways modulation in SOD1-G93A and FUS-associated amyotrophic lateral sclerosis models.

Neurotherapeutics · 2024 · PMC11070272 · PMID 38493058

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The outcomes showed a trend toward the downregulation of interleukin-1 beta (IL-1β) ( Fig. 6 i) and a significant reduction of interferon-gamma (IFN-γ) ( Fig. 6 j) in the GCM of niclosamide-treated mice versus the vehicles.

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