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Plasma IGFBP-3 and IGFBP-5 levels are decreased during acute manic episodes in bipolar disorder patients.

Front Pharmacol · 2024 · PMC11076695 · PMID 38720780

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This could be somehow in line with our findings since our patients who responded to the pharmacological treatment showed a general reduction in MCP-1 levels, although it did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.