A similar trend was observed in AML (22.7% vs 18.7%; P = .58) but did not reach statistical significance in part due to the higher prevalence of seropositive RA in AML compared with MDS (78% vs 29%; P = .03), and the lack of association of seropositive RA with IDH mutation.
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IDH-mutant myeloid neoplasms are associated with seronegative rheumatoid arthritis and innate immune activation.
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