Although the difference between the HCRA and HCR groups did not reach statistical significance, there was a slight increase in mucous layer thickness in the HCRA group compared to the HCR group, which could be attributed to the inherent ability of A. muciniphila to stimulate mucous layer growth ( 29 ).
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Capsaicin modulates Akkermansia muciniphila abundance by enhancing MUCIN2 levels in mice fed with high-fat diets.
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