RAD51 as an immunohistochemistry-based marker of poly(ADP-ribose) polymerase inhibitor resistance in ovarian cancer.

Front Oncol · 2024 · PMC11079140 · PMID 38725623

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showed a trendno p-value reported

Based on the matched ctDNA analysis, patients who had HR restoration as a resistance mechanism showed a trend of higher RAD51 H-scores ( Figure 4B ).

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a decreasing trendno p-value reported

In these patients with high pre-PARPi RAD51 H-scores, RAD51 H-score did not necessarily increase post-treatment, with several instances showing a decreasing trend.

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