Divergent cardiac and renal effects of miR-181c-5p inhibition in a rodent heart failure model.

Finally, this short-term study might not capture the long-term effects of miR-181c-5p modulation on HF progression, and diastolic dysfunction was only mildly affected in the mouse model on echocardiography (E/A and E/e’ did not reach statistical significance). 4.2.

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